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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cell division cycle 7-related protein kinase | ||
| Ligand | BDBM185849 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.5±n/a | ||
| Ki | 3.4±n/a nM | ||
| Comments | extracted | ||
| Citation |  Akritopoulou-Zanze, I; Wakefield, BD; Mack, H; Turner, SC; Gasiecki, AF; Gracias, VJ; Sarris, KA; Kalvin, DM; Michmerhuizen, MJ; Shuai, Q; Patel, JR; Bakker, MH; Teusch, N; Johnson, EF; Kovar, PJ; Djuric, SW; Long, AJ; Vasudevan, A; George, DM; Wang, L; Li, B; Moore, NS; Hobson, AD; Woods, KW; Miyashiro, JM; Swann, Jr., SL; Penning, TD 5-substituted indazoles as kinase inhibitors US Patent US9163007 Publication Date 10/20/2015 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cell division cycle 7-related protein kinase | |||
| Name: | Cell division cycle 7-related protein kinase | ||
| Synonyms: | CDC7 | CDC7-related kinase | CDC7L1 | CDC7_HUMAN | Cell division cycle 7-related protein kinase (CDC7) | HsCdc7 | huCdc7 | ||
| Type: | Protein | ||
| Mol. Mass.: | 63908.16 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O00311 | ||
| Residue: | 574 | ||
| Sequence: |
| ||
| BDBM185849 | |||
| n/a | |||
| Name | BDBM185849 | ||
| Synonyms: | US9163007, 163 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H20N6 | ||
| Mol. Mass. | 380.4451 | ||
| SMILES | Cc1ccccc1-c1c(nnn1Cc1ccccc1)-c1ccc2[nH]nc(N)c2c1 |(11.93,-1.26,;10.78,-.23,;11.1,1.27,;9.96,2.3,;8.49,1.83,;8.17,.32,;9.32,-.71,;9,-2.22,;7.59,-2.84,;7.75,-4.37,;9.26,-4.69,;10.03,-3.36,;11.56,-3.2,;12.47,-4.45,;14,-4.28,;14.9,-5.53,;14.28,-6.94,;12.74,-7.1,;11.84,-5.85,;6.26,-2.07,;6.26,-.53,;4.92,.24,;3.59,-.53,;2.13,-.06,;1.22,-1.3,;2.13,-2.55,;1.65,-4.01,;3.59,-2.07,;4.92,-2.84,)| | ||
| Structure | 
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