| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division protein FtsZ |
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| Ligand | BDBM50439496 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | GTPase Activity Assay |
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| pH | 6.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 36000±7000 nM |
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| Comments | extracted |
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| Citation |  Bewley, CA; Wipf, P Chrysophaentin analogs that inhibit FtsZ protein US Patent US9169182 Publication Date 10/27/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Cell division protein FtsZ |
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| Name: | Cell division protein FtsZ |
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| Synonyms: | FTSZ_ECOLI | ftsZ | sfiB | sulB |
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| Type: | Protein |
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| Mol. Mass.: | 40305.83 |
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| Organism: | Escherichia coli |
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| Description: | P0A9A6 |
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| Residue: | 383 |
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| Sequence: | MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNTDAQALRKTAVGQTIQI
GSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAAGMGGGTGTGAAPVVAEVA
KDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSLITIPNDKLLKVLGRGISLLD
AFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMSEMGYAMMGSGVASGEDRAEEAA
EMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFETVGNTIRAFASDNATVVIGTSLDP
DMNDELRVTVVATGIGMDKRPEITLVTNKQVQQPVMDRYQQHGMAPLTQEQKPVAKVVND
NAPQTAKEPDYLDIPAFLRKQAD
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| BDBM50439496 |
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| n/a |
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| Name | BDBM50439496 |
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| Synonyms: | CHEMBL2418096 | US9169182, J23 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18Cl2O4 |
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| Mol. Mass. | 369.239 |
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| SMILES | COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl |
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| Structure | 
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