| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nuclear factor NF-kappa-B p105 subunit |
|---|
| Ligand | BDBM191746 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Cellular Firefly Luciferase Assay (NFkB) |
|---|
| IC50 | 4200±n/a nM |
|---|
| Citation |  Vander Jagt, DL; Deck, LM; Abcouwer, SF; Orlando, RA; Royer, RE; Weber, WM; Bobrovnikova-Marjon, EV; Hunsaker, LA Therapeutic curcumin derivatives US Patent US9187397 Publication Date 11/17/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Nuclear factor NF-kappa-B p105 subunit |
|---|
| Name: | Nuclear factor NF-kappa-B p105 subunit |
|---|
| Synonyms: | NFKB1 | NFKB1_HUMAN | Nuclear factor NF-kappa-B (NF-kB) | Nuclear factor NF-kappa-B complex | Nuclear factor NF-kappa-B p105 subunit |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 105329.57 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P19838 |
|---|
| Residue: | 968 |
|---|
| Sequence: | MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV
CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCED
GICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQA
EGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY
DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDF
SPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQ
RKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITFH
PGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNGE
VTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQD
ENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVED
LLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMM
SNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGT
TPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMAT
SWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLG
LGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQ
AHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQ
EGPLEGKI
|
|
|
|---|
| BDBM191746 |
|---|
| n/a |
|---|
| Name | BDBM191746 |
|---|
| Synonyms: | US9187397, 20q |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H14O3 |
|---|
| Mol. Mass. | 266.2913 |
|---|
| SMILES | Oc1ccccc1\C=C\C(=O)\C=C\c1ccccc1O |
|---|
| Structure | 
|
|---|
Search and Browse
