| Reaction Details |
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 | Report a problem with these data |
| Target | Transcription factor Jun |
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| Ligand | BDBM191749 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cellular Firefly Luciferase Assay (AP-1) |
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| IC50 | 6000±n/a nM |
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| Citation |  Vander Jagt, DL; Deck, LM; Abcouwer, SF; Orlando, RA; Royer, RE; Weber, WM; Bobrovnikova-Marjon, EV; Hunsaker, LA Therapeutic curcumin derivatives US Patent US9187397 Publication Date 11/17/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Transcription factor Jun |
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| Name: | Transcription factor Jun |
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| Synonyms: | AP1 | Activator protein 1 | JUN | JUN_HUMAN | Proto-oncogene c-JUN | Transcription factor AP-1 | Transcription factor AP1 | V-jun avian sarcoma virus 17 oncogene homolog | p39 |
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| Type: | n/a |
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| Mol. Mass.: | 35683.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P05412 |
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| Residue: | 331 |
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| Sequence: | MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDL
LTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAE
LHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGA
LSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETP
PLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANM
LREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
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| BDBM191749 |
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| n/a |
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| Name | BDBM191749 |
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| Synonyms: | US9187397, 2 | US9187397, 6a |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22O6 |
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| Mol. Mass. | 382.4065 |
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| SMILES | COc1cc(\C=C\C(\O)=C(/C)C(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O |
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| Structure | 
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