| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transcription factor Jun |
|---|
| Ligand | BDBM50067033 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Cellular Firefly Luciferase Assay (AP-1) |
|---|
| IC50 | 7300±n/a nM |
|---|
| Citation |  Vander Jagt, DL; Deck, LM; Abcouwer, SF; Orlando, RA; Royer, RE; Weber, WM; Bobrovnikova-Marjon, EV; Hunsaker, LA Therapeutic curcumin derivatives US Patent US9187397 Publication Date 11/17/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Transcription factor Jun |
|---|
| Name: | Transcription factor Jun |
|---|
| Synonyms: | AP1 | Activator protein 1 | JUN | JUN_HUMAN | Proto-oncogene c-JUN | Transcription factor AP-1 | Transcription factor AP1 | V-jun avian sarcoma virus 17 oncogene homolog | p39 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 35683.24 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P05412 |
|---|
| Residue: | 331 |
|---|
| Sequence: | MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDL
LTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAE
LHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGA
LSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETP
PLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANM
LREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
|
|
|
|---|
| BDBM50067033 |
|---|
| n/a |
|---|
| Name | BDBM50067033 |
|---|
| Synonyms: | (2E,6E)-2,6-bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone | 2,6-Bis((3-methoxy-4-hydroxyphenyl)methylene)-cyclohexanone | 2,6-Bis-(4-hydroxy-3-methoxy-benzylidene)-cyclohexanone | 2,6-Bis-[1-(4-hydroxy-3-methoxy-phenyl)-meth-(E)-ylidene]-cyclohexanone | 2,6-bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone | CHEMBL17205 | Cyclovalone | US9187397, 38a | cid_1550234 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H22O5 |
|---|
| Mol. Mass. | 366.4071 |
|---|
| SMILES | COc1cc(\C=C2/CCC\C(=C/c3ccc(O)c(OC)c3)C2=O)ccc1O |
|---|
| Structure | 
|
|---|
Search and Browse
