| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome b |
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| Ligand | BDBM192029 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cytochrome b Enzyme Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | >6.4e+4±n/a nM |
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| Comments | extracted |
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| Citation |  Vincent, BM; Langlois, JB; Srinivas, R; Lancaster, AK; Scherz-Shouval, R; Whitesell, L; Tidor, B; Buchwald, SL; Lindquist, S A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance. Cell Chem Biol23:978-991 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome b |
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| Name: | Cytochrome b |
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| Synonyms: | COB | CYB_HUMAN | CYTB | MT-CYB | MTCYB |
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| Type: | Protein |
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| Mol. Mass.: | 42724.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 380 |
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| Sequence: | MTPMRKTNPLMKLINHSFIDLPTPSNISAWWNFGSLLGACLILQITTGLFLAMHYSPDAS
TAFSSIAHITRDVNYGWIIRYLHANGASMFFICLFLHIGRGLYYGSFLYSETWNIGIILL
LATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGYSVDSPTLTRFFT
FHFILPFIIAALATLHLLFLHETGSNNPLGITSHSDKITFHPYYTIKDALGLLLFLLSLM
TLTLFSPDLLGDPDNYTLANPLNTPPHIKPEWYFLFAYTILRSVPNKLGGVLALLLSILI
LAMIPILHMSKQQSMMFRPLSQSLYWLLAADLLILTWIGGQPVSYPFTIIGQVASVLYFT
TILILMPTISLIENKMLKWA
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| BDBM192029 |
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| n/a |
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| Name | BDBM192029 |
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| Synonyms: | Inz-20 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13N3O2 |
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| Mol. Mass. | 291.304 |
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| SMILES | COC(=O)Cn1nc(-c2ccccc2C#N)c2ccccc12 |
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| Structure | 
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