| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome b |
|---|
| Ligand | BDBM192093 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Cytochrome b Enzyme Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | 2917±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Vincent, BM; Langlois, JB; Srinivas, R; Lancaster, AK; Scherz-Shouval, R; Whitesell, L; Tidor, B; Buchwald, SL; Lindquist, S A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance. Cell Chem Biol23:978-991 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome b |
|---|
| Name: | Cytochrome b |
|---|
| Synonyms: | COB | CYB_HUMAN | CYTB | MT-CYB | MTCYB |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 42724.13 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 380 |
|---|
| Sequence: | MTPMRKTNPLMKLINHSFIDLPTPSNISAWWNFGSLLGACLILQITTGLFLAMHYSPDAS
TAFSSIAHITRDVNYGWIIRYLHANGASMFFICLFLHIGRGLYYGSFLYSETWNIGIILL
LATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGYSVDSPTLTRFFT
FHFILPFIIAALATLHLLFLHETGSNNPLGITSHSDKITFHPYYTIKDALGLLLFLLSLM
TLTLFSPDLLGDPDNYTLANPLNTPPHIKPEWYFLFAYTILRSVPNKLGGVLALLLSILI
LAMIPILHMSKQQSMMFRPLSQSLYWLLAADLLILTWIGGQPVSYPFTIIGQVASVLYFT
TILILMPTISLIENKMLKWA
|
|
|
|---|
| BDBM192093 |
|---|
| n/a |
|---|
| Name | BDBM192093 |
|---|
| Synonyms: | Inz-84 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H31FN6O |
|---|
| Mol. Mass. | 462.5623 |
|---|
| SMILES | Cc1cccc2c(nn(Cc3nnn(C)n3)c12)-c1cc(OCCCC2CCCCC2)ccc1F |
|---|
| Structure | 
|
|---|
Search and Browse
