| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 13 |
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| Ligand | BDBM50249406 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Immobilized Metal Affinity Polarization (IMAP) Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 82.72±n/a nM |
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| Comments | extracted |
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| Citation |  Holtzman, M; Romero, A; Alevy, Y; Patel, A; Brett, T; Patel, D Anti-mucus drugs and uses therefor US Patent US9187470 Publication Date 11/17/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Mitogen-activated protein kinase 13 |
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| Name: | Mitogen-activated protein kinase 13 |
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| Synonyms: | MAP kinase p38 delta | MAPK13 | MK13_HUMAN | Mitogen-activated protein kinase 13 | Mitogen-activated protein kinase 13 (MAPK13) | Mitogen-activated protein kinase p38 | Mitogen-activated protein kinase p38 delta | PRKM13 | SAPK4 | Stress-activated protein kinase 4 | p38 delta/gamma |
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| Type: | Enzyme |
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| Mol. Mass.: | 42097.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O15264 |
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| Residue: | 365 |
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| Sequence: | MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGM
EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAA
QALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRR
SGMKL
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| BDBM50249406 |
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| n/a |
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| Name | BDBM50249406 |
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| Synonyms: | 1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-(4-(pyridin-4-yloxy)phenyl)urea | CHEMBL472620 | US9187470, 61 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N5O2 |
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| Mol. Mass. | 365.4289 |
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| SMILES | Cn1nc(cc1NC(=O)Nc1ccc(Oc2ccncc2)cc1)C(C)(C)C |
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| Structure | 
|
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