Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | DNA polymerase | ||
| Ligand | BDBM51312 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 310.15±n/a K | ||
| IC50 | 5900±n/a nM | ||
| Comments | extracted | ||
| Citation |  Ricciardi, RP Therapeutic compounds for blocking DNA synthesis of POX viruses US Patent US9211296 Publication Date 12/15/2015 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| DNA polymerase | |||
| Name: | DNA polymerase | ||
| Synonyms: | DNA Synthesis | DPOL_VACCW | OPG071 | POL | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 116939.47 | ||
| Organism: | Vaccinia virus (strain WR) | ||
| Description: | P06856 | ||
| Residue: | 1006 | ||
| Sequence: |
| ||
| BDBM51312 | |||
| n/a | |||
| Name | BDBM51312 | ||
| Synonyms: | 3-[(8,9-dimethoxy-2-phenyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)amino]propyl-diethyl-amine | MLS000520480 | N-(8,9-dimethoxy-2-phenyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-N',N'-diethyl-propane-1,3-diamine | N-(8,9-dimethoxy-2-phenyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-N',N'-diethylpropane-1,3-diamine | SMR000130891 | US9211296, Table 7, Compd: 11 | cid_6622924 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H30N6O2 | ||
| Mol. Mass. | 434.534 | ||
| SMILES | CCN(CC)CCCNc1nc2cc(OC)c(OC)cc2c2nc(nn12)-c1ccccc1 | ||
| Structure | 
| ||