| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 4 |
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| Ligand | BDBM196937 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Pharmacological Assay |
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| EC50 | 62500±20500 nM |
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| Citation |  Acher, F; Pin, J; Goudet, C; Eschalier, A; Busserolles, J; Rigault, D; Lemasson, I; Cesarini, S; Commare, B Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereof US Patent US9212196 Publication Date 12/15/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Metabotropic glutamate receptor 4 |
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| Name: | Metabotropic glutamate receptor 4 |
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| Synonyms: | GRM4_RAT | Gprc1d | Grm4 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 4 (mGlu4) | Mglur4 | mGlu4 | metabotropic glutamate 4 | metabotropic glutamate 4a |
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| Type: | Enzyme |
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| Mol. Mass.: | 101849.79 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P31423 |
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| Residue: | 912 |
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| Sequence: | MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR
GSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL
TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA
STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQ
KSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRA
NQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI
WFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY
QLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCW
HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIA
ATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG
LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVV
DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET
FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP
KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALAT
KQTYVTYTNHAI
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| BDBM196937 |
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| n/a |
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| Name | BDBM196937 |
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| Synonyms: | US9212196, Derivative 33 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H17F3NO7P |
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| Mol. Mass. | 399.2563 |
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| SMILES | N[C@H](CCP(O)(=O)Cc1ccc(OCC(O)=O)c(c1)C(F)(F)F)C(O)=O |r| |
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| Structure | 
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