| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-1 |
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| Ligand | BDBM206562 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PIM Kinase Binding Activity Assay |
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| pH | 7.2±n/a |
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| Ki | 0.00806±n/a nM |
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| Comments | extracted |
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| Citation |  Do, S; Hu, H; Kolesnikov, A; Lee, W; Tsui, VH; Wang, X; Wen, Z Pyrazolo[3,4-c]pyridine compounds and methods of use US Patent US9260425 Publication Date 2/16/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Serine/threonine-protein kinase pim-1 |
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| Name: | Serine/threonine-protein kinase pim-1 |
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| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) |
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| Type: | Protein |
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| Mol. Mass.: | 35681.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11309 |
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| Residue: | 313 |
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| Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK
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|
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| BDBM206562 |
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| n/a |
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| Name | BDBM206562 |
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| Synonyms: | US9260425, 315 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23N7 |
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| Mol. Mass. | 385.4649 |
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| SMILES | Cc1ccc(nc1N1CCC[C@H](N)C1)-c1n[nH]c2cnc(cc12)-c1cccnc1 |r| |
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| Structure | 
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