| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen [starch] synthase, muscle |
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| Ligand | BDBM212196 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Glycogen Synthase Activity Assay |
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| pH | 7.3±n/a |
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| Temperature | 303.15±n/a K |
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| EC50 | 810±n/a nM |
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| Comments | extracted |
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| Citation |  Nakagawa, T; Matsumoto, K; Takeshita, S; Yoshida, T; Tokumasu, M; Inoue, H; Kobayashi, K Pharmaceutical composition for treating diabetes US Patent US9290487 Publication Date 3/22/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen [starch] synthase, muscle |
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| Name: | Glycogen [starch] synthase, muscle |
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| Synonyms: | GYS | GYS1 | GYS1_HUMAN | Glycogen [starch] synthase, muscle | Glycogen synthase (GYS1) | Muscle glycogen synthase |
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| Type: | Enzyme |
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| Mol. Mass.: | 83779.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P13807 |
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| Residue: | 737 |
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| Sequence: | MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGD
NYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVG
ASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKPHVVAHFH
EWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYH
RYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQS
KARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQ
TVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVGSLPDMNKML
DKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPE
FLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEE
HIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKY
LGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSRHSSPHQSEDE
EDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASCTSSTSGSKRNSVDTATSSSLS
TPSEPLSPTSSLGEERN
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| BDBM212196 |
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| n/a |
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| Name | BDBM212196 |
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| Synonyms: | US9290487, compound of Ex. 44 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H23F2NO6 |
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| Mol. Mass. | 495.4714 |
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| SMILES | COC(=O)c1cc(F)c(F)cc1-c1ccc(OCc2cccc(c2)C(=O)N2CCC[C@H]2C(O)=O)cc1 |r| |
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| Structure | 
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