| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glycogen [starch] synthase, muscle |
|---|
| Ligand | BDBM212211 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Glycogen Synthase Activity Assay |
|---|
| pH | 7.3±n/a |
|---|
| Temperature | 303.15±n/a K |
|---|
| EC50 | 150±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Nakagawa, T; Matsumoto, K; Takeshita, S; Yoshida, T; Tokumasu, M; Inoue, H; Kobayashi, K Pharmaceutical composition for treating diabetes US Patent US9290487 Publication Date 3/22/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glycogen [starch] synthase, muscle |
|---|
| Name: | Glycogen [starch] synthase, muscle |
|---|
| Synonyms: | GYS | GYS1 | GYS1_HUMAN | Glycogen [starch] synthase, muscle | Glycogen synthase (GYS1) | Muscle glycogen synthase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 83779.52 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P13807 |
|---|
| Residue: | 737 |
|---|
| Sequence: | MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGD
NYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVG
ASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKPHVVAHFH
EWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYH
RYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQS
KARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQ
TVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVGSLPDMNKML
DKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPE
FLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEE
HIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKY
LGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSRHSSPHQSEDE
EDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASCTSSTSGSKRNSVDTATSSSLS
TPSEPLSPTSSLGEERN
|
|
|
|---|
| BDBM212211 |
|---|
| n/a |
|---|
| Name | BDBM212211 |
|---|
| Synonyms: | US9290487, compound of Ex. 59 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H19F2NO5 |
|---|
| Mol. Mass. | 463.4296 |
|---|
| SMILES | OC(=O)[C@@H]1CCN1C(=O)c1cccc(COc2ccc(cc2)-c2cc(F)c(F)c3ccoc23)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
