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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Plasminogen [101-181] | ||
| Ligand | BDBM290335 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Biacore Assay | ||
| pH | 7±n/a | ||
| IC50 | 15.0±n/a nM | ||
| Comments | extracted | ||
| Citation |  Haßfeld, J; Kinzel, T; Köbberling, J; Cancho-Grande, Y; Beyer, K; Röhrig, S; Köllnberger, M; Sperzel, M; Burkhardt, N; Schlemmer, K; Stegmann, C; Schuhmacher, J; Werner, M; Ellermann, M (Aza)pyridopyrazolopyrimidinones and indazolopyrimidinones and their use US Patent US10098883 Publication Date 10/16/2018 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Plasminogen [101-181] | |||
| Name: | Plasminogen [101-181] | ||
| Synonyms: | PLG | PLMN_HUMAN | Plasminogen (aa 101-181) | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 9281.08 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P00747[101-181] | ||
| Residue: | 81 | ||
| Sequence: |
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| BDBM290335 | |||
| n/a | |||
| Name | BDBM290335 | ||
| Synonyms: | 10-(2,6-Difluorophenyl)-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-2(1H)-one hydrochloride | US10098883, Example 78 | US10668071, Example 78 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H18F2N4O | ||
| Mol. Mass. | 380.3906 | ||
| SMILES | Fc1cccc(F)c1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 |(1.55,5.36,;2.64,4.27,;4.13,4.67,;5.22,3.58,;4.82,2.09,;3.33,1.69,;2.93,.21,;2.24,2.78,;.7,2.78,;.08,4.19,;-1.46,4.35,;-2.36,3.1,;-1.73,1.7,;-2.36,.29,;-1.22,-.74,;-1.22,-2.28,;.12,-3.05,;1.45,-2.28,;2.78,-3.05,;1.45,-.74,;.12,.03,;-.2,1.54,;-2.55,-3.05,;-3.88,-2.28,;-5.22,-3.05,;-5.22,-4.59,;-3.88,-5.36,;-2.55,-4.59,)| | ||
| Structure | 
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