Reaction Details |
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Target | Iodotyrosine deiodinase [1-228] |
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Ligand | BDBM37633 |
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Substrate/Competitor | n/a |
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Meas. Tech. | IYD Binding Assay |
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Kd | 8.2e+3± 5e+2 nM |
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Citation | Ingavat, N; Kavran, JM; Sun, Z; Rokita, SE Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase. Biochemistry56:1130-1139 (2017) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Iodotyrosine deiodinase [1-228] |
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Name: | Iodotyrosine deiodinase [1-228] |
Synonyms: | IYD | IYD_HALH1 | Iodotyrosine deiodinase (IYD) |
Type: | Enzyme |
Mol. Mass.: | 26134.19 |
Organism: | Haliscomenobacter hydrossis |
Description: | F4KU78[1-228] |
Residue: | 228 |
Sequence: | MKQKPAFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTA
PSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESYNGRMSNEWLEDLQPFGTDWHKPFLE
IAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFL
QKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYHHHHHH
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BDBM37633 |
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n/a |
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Name | BDBM37633 |
Synonyms: | (2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic acid | (2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid | (2S)-2-azanyl-3-(3-iodanyl-4-oxidanyl-phenyl)propanoic acid | 3-IODO-L-TYROSINE | 3-Iodo-L-tyrosine (I-Tyr) | MLS000069664 | Monoiodotyrosine | SMR000059143 | cid_439744 |
Type | Small organic molecule |
Emp. Form. | C9H10INO3 |
Mol. Mass. | 307.0851 |
SMILES | N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O |
Structure |
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