| Reaction Details |
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 | Report a problem with these data |
| Target | Opioid growth factor receptor-like protein 1 |
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| Ligand | BDBM220358 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro ORL-1 Receptor Functional Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| EC50 | 319±28 nM |
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| Comments | extracted |
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| Citation |  Tafesse, L; Tsuno, N; Zhou, X Azetidine-substituted quinoxalines as opioid receptor like-1 modulators US Patent US9290488 Publication Date 3/22/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Opioid growth factor receptor-like protein 1 |
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| Name: | Opioid growth factor receptor-like protein 1 |
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| Synonyms: | OGFRL1 | OGRL1_HUMAN | Opioid Receptor-Like Receptor (ORL-1) | Opioid growth factor receptor-like protein 1 (ORL-1) | Opioid growth factor receptor-like protein 1 (ORL1) | Opioid receptor-like (ORL-1) | Opioid receptor-like (ORL1) | Opioid receptor-like protein 1 (OGL1) | Opioid receptor-like receptor (ORL1) |
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| Type: | Protein |
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| Mol. Mass.: | 51247.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q5TC84 |
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| Residue: | 451 |
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| Sequence: | MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEEPGPGGGSEGPGQESEQPAQPPEQAGGR
PGASPAPDEDAEAAGAEQGGDSTEATAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSN
LRFYKNKIPFKPDGVYIEEVLSKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYE
IEEFKKTKEAIRRFLLAYKMMLEFFGIKLTDKTGNVARAVNWQERFQHLNESQHNYLRIT
RILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFA
QKHYTPSENFIWGPPRKEQSEGSKAQKMSSPLASSHNSQTSMHKKAKDSKNSSSAVHLNS
KTAEDKKVAPKEPVEETDRPSPEPSNEAAKPRNTEKDSNAENMNSQPEKTVTTPTEKKES
VSPENNEEGGNDNQDNENPGNTNCHDVVLVQ
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| BDBM220358 |
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| n/a |
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| Name | BDBM220358 |
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| Synonyms: | US9290488, B2a(i) |
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| Type | Small organic molecule |
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| Emp. Form. | C29H38N4O3 |
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| Mol. Mass. | 490.637 |
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| SMILES | OC(=O)[C@H]1CCN1c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@@H]2C[C@H]3CCC[C@H](C3)C2)c1=O |r,THB:25:24:16.17.23:19.21.20| |
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| Structure | 
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