| Reaction Details |
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 | Report a problem with these data |
| Target | Oligo-1,6-glucosidase IMA1 |
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| Ligand | BDBM222212 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | α-Glucosidase Inhibition Assay |
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| IC50 | 2.223e+4± 2e+1 nM |
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| Citation |  Chaudhry, F; Naureen, S; Huma, R; Shaukat, A; Al-Rashida, M; Asif, N; Ashraf, M; Munawar, MA; Khan, MA In search of new a-glucosidase inhibitors: Imidazolylpyrazole derivatives. Bioorg Chem71:102-109 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oligo-1,6-glucosidase IMA1 |
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| Name: | Oligo-1,6-glucosidase IMA1 |
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| Synonyms: | α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase |
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| Type: | Protein |
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| Mol. Mass.: | 68577.59 |
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| Organism: | Saccharomyces cerevisiae S288c (Baker's yeast) |
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| Description: | n/a |
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| Residue: | 589 |
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| Sequence: | MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWIS
PFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWF
KESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCS
TQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQS
SDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSEL
FNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRF
GDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIK
EEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGIN
VEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAA
LNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
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| BDBM222212 |
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| n/a |
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| Name | BDBM222212 |
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| Synonyms: | 4-(4,5-Diphenyl-1H-imidazol-2-yl)-1,3-diphenyl-1H-pyrazole (2a) |
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| Type | Small organic molecule |
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| Emp. Form. | C30H22N4 |
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| Mol. Mass. | 438.5225 |
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| SMILES | c1c(-c2nc(c([nH]2)-c2ccccc2)-c2ccccc2)c(nn1-c1ccccc1)-c1ccccc1 |
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| Structure | 
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