| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
|---|
| Ligand | BDBM251686 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro LPA1 Receptor Assay |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | 30.0±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Buffham, W; Canning, H; Davenport, R; Farnaby, W; Mack, S; Parmar, A; Wright, S Amide derivatives as lysophosphatidic acid receptor antagonists US Patent US10100018 Publication Date 10/16/2018 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lysophosphatidic acid receptor 1 |
|---|
| Name: | Lysophosphatidic acid receptor 1 |
|---|
| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41120.55 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q92633 |
|---|
| Residue: | 364 |
|---|
| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
|
|
|
|---|
| BDBM251686 |
|---|
| n/a |
|---|
| Name | BDBM251686 |
|---|
| Synonyms: | US10100018, Example 22 | US9464060, 22 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H25NO4 |
|---|
| Mol. Mass. | 415.481 |
|---|
| SMILES | Cc1ccccc1Oc1ccc(cc1)C(=O)N(CC1CC1)Cc1ccc(cc1)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
