| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-glucosidase MAL32 |
|---|
| Ligand | BDBM23406 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | α-Glucosidase Inhibition Assay |
|---|
| pH | 6.8±n/a |
|---|
| Temperature | 274.15±n/a K |
|---|
| IC50 | 1.3098e+5± 4.12e+3 nM |
|---|
| Comments | extracted |
|---|
| Citation |  Gupta, SJ; Dutta, S; Gajbhiye, RL; Jaisankar, P; Sen, AK Synthesis, in vitro evaluation and molecular docking studies of novel amide linked triazolyl glycoconjugates as new inhibitors of a-glucosidase. Bioorg Chem72:11-20 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-glucosidase MAL32 |
|---|
| Name: | Alpha-glucosidase MAL32 |
|---|
| Synonyms: | Alpha-glucosidase MAL32 | MAL32 | MAL32_YEAST | MAL3S | Maltase | alpha-Glucosidase (α-Glucosidase) | alpha-Glucosidase (alpha-Glu) | alpha-Glucosidase (α-Glucosidase) |
|---|
| Type: | Hydrolase |
|---|
| Mol. Mass.: | 68132.36 |
|---|
| Organism: | Saccharomyces cerevisiae |
|---|
| Description: | Purchased from Wako Fine Chemicals Co. Ltd. |
|---|
| Residue: | 584 |
|---|
| Sequence: | MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCP
FYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFK
ESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASR
QVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHP
NWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSF
THVELGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADD
SPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSF
GKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFFLNESFEQGINVEQ
ESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNF
SGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
|
|
|
|---|
| BDBM23406 |
|---|
| n/a |
|---|
| Name | BDBM23406 |
|---|
| Synonyms: | (3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-2,3,4-triol | Acarbose | US11292789, Acarbose |
|---|
| Type | Carbohydrate |
|---|
| Emp. Form. | C25H43NO18 |
|---|
| Mol. Mass. | 645.6048 |
|---|
| SMILES | C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |t:37| |
|---|
| Structure | 
|
|---|
Search and Browse
