| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma [182-505]/Regulatory protein GAL4 [1-147] |
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| Ligand | BDBM222674 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Activation Assay |
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| EC50 | 1360±n/a nM |
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| Citation |  Miura, T; Sato, S; Yamada, H; Tagashira, J; Watanabe, T; Sekimoto, R; Ishida, R; Aoki, H; Ohgiya, T Phenylpyridine derivative and drug containing same US Patent US9315493 Publication Date 4/19/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor gamma [182-505]/Regulatory protein GAL4 [1-147] |
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| Name: | Peroxisome proliferator-activated receptor gamma [182-505]/Regulatory protein GAL4 [1-147] |
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| Synonyms: | PPARgamma2 - DNA binding domain of Gal4 |
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| Type: | DNA-Protein |
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| Mol. Mass.: | n/a |
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| Description: | n/a |
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| Components: | This complex has 2 components. |
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| Component 1 |
| Name: | Regulatory protein GAL4 [1-147] |
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| Synonyms: | DNA-binding transcription factor (GAl4) | GAL4 | GAL4_YEAST |
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| Type: | DNA Binding |
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| Mol. Mass.: | 16874.50 |
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| Organism: | Saccharomyces bayanus (Yeast) |
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| Description: | amino acids 1 to 147 |
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| Residue: | 147 |
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| Sequence: | MKLLSSIEQACDICRLKKLKCSKEKPKCAKCLKNNWECRYSPKTKRSPLTRAHLTEVESR
LERLEQLFLLIFPREDLDMILKMDSLQDIKALLTGLFVQDNVNKDAVTDRLASVETDMPL
TLRQHRISATSSSEESSNKGQRQLTVS
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| Component 2 |
| Name: | Peroxisome proliferator-activated receptor gamma [182-505] |
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| Synonyms: | NR1C3 | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) |
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| Type: | Protein |
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| Mol. Mass.: | 37077.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | amino acids 182 to 505 |
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| Residue: | 324 |
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| Sequence: | IHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRA
LAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQ
SKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASL
MNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIIL
SGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLL
QVIKKTETDMSLHPLLQEIYKDLY
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| BDBM222674 |
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| n/a |
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| Name | BDBM222674 |
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| Synonyms: | US9315493, 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H33N9O2 |
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| Mol. Mass. | 551.6421 |
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| SMILES | CCCCc1nc(C(C)C)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1nnn[nH]1 |
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| Structure | 
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