Reaction Details |
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Target | Leukotriene C4 synthase |
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Ligand | BDBM223266 |
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Substrate/Competitor | LTC4 |
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Meas. Tech. | In Vitro hLTC4 Synthase Enzyme Assay (Test A) |
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pH | 7.8±n/a |
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IC50 | 81±n/a nM |
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Comments | extracted |
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Citation | Ronn, R; Lindh, CJ; Ringberg, E; Andersson, HB; Nilsson, P; Schaal, WR; Rosenschold, MM; Nikitidis, A; Nikitidis, G; Johannesson, P; Tyrcha, C Compounds and uses US Patent US20160326143 Publication Date 11/10/2016 |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Leukotriene C4 synthase |
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Name: | Leukotriene C4 synthase |
Synonyms: | LTC4 synthase | LTC4S | LTC4S_HUMAN | Leukotriene-C(4) synthase |
Type: | PROTEIN |
Mol. Mass.: | 16575.59 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_961179 |
Residue: | 150 |
Sequence: | MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
LAALGLLAHFLPAALRAALLGRLRTLLPWA
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BDBM223266 |
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LTC4 |
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Name | BDBM223266 |
Synonyms: | 2-(5-((4-Chlorophenyl)(cyclopropylmethyl)amino)-3-methoxypicolinoyl)-N-((4-methoxyphenyl)sulfonyl)-cyclopropanecarboxamide | US20160326143, 41 | US9657001, 41 |
Type | Small Organic Molecule |
Emp. Form. | C28H28ClN3O6S |
Mol. Mass. | 570.056 |
SMILES | COc1ccc(cc1)S(=O)(=O)NC(=O)C1CC1C(=O)c1ncc(cc1OC)N(CC1CC1)c1ccc(Cl)cc1 |
Structure |
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