Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetInterleukin-2
LigandBDBM161857
Substrate/Competitorn/a
Meas. Tech. IL-2 ELISA Assay
EC50<100±n/a nM
Citation Singh, RDuncton, MZhang, JAlvarez, STso, KHolland, SYen, RKolluri, RHeckrodt, TChen, YMasuda, ELi, HPayan, DGKelley, R Protein kinase C inhibitors and uses thereof US Patent US9682976 Publication Date 6/20/2017
More Info.:Get all data from this article,  Assay Method
 
Interleukin-2
Name:Interleukin-2
Synonyms:IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:Enzyme
Mol. Mass.:17630.05
Organism:Homo sapiens (Human)
Description:P60568
Residue:153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRML
TFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSE
TTFMCEYADETATIVEFLNRWITFCQSIISTLT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM161857
n/a
NameBDBM161857
Synonyms:US9682976, 289
TypeSmall organic molecule
Emp. Form.C26H36FN9O2
Mol. Mass.525.6215
SMILESCc1ccc(Nc2ncc(F)c(N[C@@H]3C[C@@H]4CCCN4C(C)(C)C3)n2)cc1-n1nnn(CC(C)(C)O)c1=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: