| Reaction Details |
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 | Report a problem with these data |
| Target | RAC-alpha serine/threonine-protein kinase [1-123] |
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| Ligand | BDBM50304371 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SPR Competitive Binding Assay |
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| Ki | >50000±n/a nM |
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| Citation |  Mahadevan, D; Meuillet, EJ; Mash, Jr., EA; Gokhale, VM; Powis, G; Zhang, S Small molecule inhibitors of the pleckstrin homology domain and methods for using same US Patent US9320734 Publication Date 4/26/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| RAC-alpha serine/threonine-protein kinase [1-123] |
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| Name: | RAC-alpha serine/threonine-protein kinase [1-123] |
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| Synonyms: | AKT1 | AKT1_HUMAN | PKB | RAC | RAC-alpha serine/threonine-protein kinase (Akt) |
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| Type: | Enzyme |
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| Mol. Mass.: | 14664.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PLECKSTRIN HOMOLOGY DOMAIN RESIDUES 1-123 (PH Domain) |
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| Residue: | 123 |
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| Sequence: | MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
RSG
|
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|
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| BDBM50304371 |
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| n/a |
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| Name | BDBM50304371 |
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| Synonyms: | CHEMBL611216 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfamoyl)phenyl)-2-(2-(2-methoxyethoxy)ethoxy)acetamide | US9320734, 103 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20N4O6S2 |
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| Mol. Mass. | 416.472 |
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| SMILES | COCCOCCOCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1 |
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| Structure | 
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