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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM223526 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Inhibition Assay | ||
| IC50 | <50±n/a nM | ||
| Citation |  Ahn, JH; Pagire, HS; Rhee, SD; Kim, KY; Jung, WH; Bae, M; Song, JS; Kim, K; Kwak, HJ Beta-alanine derivatives, pharmaceutically acceptable salts thereof, and pharmaceutical composition comprising same as active ingredient US Patent US9321728 Publication Date 4/26/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
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| BDBM223526 | |||
| n/a | |||
| Name | BDBM223526 | ||
| Synonyms: | US9321728, 94 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H31ClN2O4 | ||
| Mol. Mass. | 519.031 | ||
| SMILES | OC(=O)C[C@H]1CCC(CC1)c1ccc(NC(=O)CCNC(=O)c2ccc(c(Cl)c2)-c2ccccc2)cc1 |r,wD:4.3,$;;;;;;;;;;;;;;HN;;;;;HN;;;;;;;;;;;;;;;;;$,(13.34,-5,;12,-4.23,;12,-2.69,;10.67,-5,;9.34,-4.23,;9.34,-2.69,;8,-1.93,;6.67,-2.69,;6.67,-4.23,;8,-5,;5.33,-1.93,;4,-2.69,;2.67,-1.93,;2.67,-.38,;1.33,.38,;,-.38,;,-1.93,;-1.33,.38,;-2.67,-.38,;-4,.38,;-5.33,-.38,;-5.33,-1.93,;-6.67,.38,;-6.67,1.93,;-8,2.69,;-9.34,1.93,;-9.34,.38,;-10.67,-.38,;-8,-.38,;-10.67,2.69,;-10.67,4.23,;-12,5,;-13.34,4.23,;-13.34,2.69,;-12,1.93,;4,.38,;5.33,-.38,)| | ||
| Structure | 
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