| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
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| Ligand | BDBM223533 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Calcium Flux Assay Using Fluorometric Imaging Plate Reader (FLIPR) Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | >30000±n/a nM |
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| Comments | extracted |
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| Citation |  Gabriel, SD; Hamilton, MM; Lucas, MC; Qian, Y; Sidduri, A N-alkyltriazole compounds as LPAR antagonists US Patent US9321738 Publication Date 4/26/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 1 |
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| Name: | Lysophosphatidic acid receptor 1 |
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| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41120.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92633 |
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| Residue: | 364 |
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| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
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| BDBM223533 |
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| n/a |
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| Name | BDBM223533 |
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| Synonyms: | US9321738, 10 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H27FN4O4 |
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| Mol. Mass. | 514.5475 |
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| SMILES | COC(=O)C1(CC1)c1ccc(cc1)-c1ccc(-c2nnn(C)c2NC(=O)O[C@H](C)c2ccccc2)c(F)c1 |r| |
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| Structure | 
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