| Reaction Details |
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 | Report a problem with these data |
| Target | DNA helicase [35-727] |
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| Ligand | BDBM200295 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | DNA-Dependent ATPase Assay |
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| pH | 8±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 3.1e+3±n/a nM |
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| Citation |  Tarique, M; Tabassum, F; Ahmad, M; Tuteja, R Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth. BMC Biochem15:9 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA helicase [35-727] |
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| Name: | DNA helicase [35-727] |
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| Synonyms: | UvrD helicase (PfUDN) |
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| Type: | Enzyme |
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| Mol. Mass.: | 81959.48 |
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| Organism: | Plasmodium falciparum |
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| Description: | N-terminal fragment of P. falciparum UvrD helicase (35-727 aa) |
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| Residue: | 693 |
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| Sequence: | NFSEEQQRIIEIPMNVNLCIIACPGSGKTSTLTARIIKSIIEEKQSIVCITFTNYAASDL
KDKIMKKINCLIDICVDNKINQKLFNNKNNKINFSLKNKCTLNNKMNKSIFKVLNTVMFI
GTIHSFCRYILYKYKGTFKILTDFINTNIIKLAFNNFYSSMMSKTKGTQPGFSTILERKS
NKASTQNCDPDKINTHNNDDNINNKNDYINNKNKNDYNNINNYDNINNYDNINNDDNINN
DDNINNDDNINNDDNINNDDDINNCGNCNQPKGIPSQLAYFINCMKNAEIKEDEEKEFYE
EEHDIQNDILNNDDNNNDEDDDDDDEFYNYLYNFKHSYEQTNDYFANEQVQSVLKKKNII
FLKKKIKLMKYIELYNIKIEINDVEKMFYEEYKKIFKKAKNIYYDFDDLLIETYRLMKDN
ADIRNKILEEWNYVFCDEFQDTNTTQFNILQFFVNHNVPSTLDQSIYTSGNLENKDIKDN
HNISMSTYKSKQYSHSVQNFFNEHKVDQQLCDQIYFDKHCNNILMQNKNQQATHKHSEEE
EEQEEEKKKNKKTKKTNTFINQQKIKTQTVLSYKQDEMSSSASSTYSYVKIEKEKKKYAL
NKIDDTYYNKKNIYSNNDEILDIENEQTFFNNNCNEKNKTKKKCNLKDRSLTVIGDDDQS
IYSFRGAHINVFYKFLKDCNCLLFKLNNNFRST
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| BDBM200295 |
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| n/a |
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| Name | BDBM200295 |
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| Synonyms: | AB00053825_07 | Ethidium bromide | cid_3624 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20N3 |
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| Mol. Mass. | 314.4031 |
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| SMILES | CC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc12 |
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| Structure | 
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