Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | DNA helicase [35-727] | ||
| Ligand | BDBM32017 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | DNA-Dependent ATPase Assay | ||
| pH | 8±0 | ||
| Temperature | 310.15±0 K | ||
| IC50 | 4.4e+3±n/a nM | ||
| Citation |  Tarique, M; Tabassum, F; Ahmad, M; Tuteja, R Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth. BMC Biochem15:9 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| DNA helicase [35-727] | |||
| Name: | DNA helicase [35-727] | ||
| Synonyms: | UvrD helicase (PfUDN) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 81959.48 | ||
| Organism: | Plasmodium falciparum | ||
| Description: | N-terminal fragment of P. falciparum UvrD helicase (35-727 aa) | ||
| Residue: | 693 | ||
| Sequence: |
| ||
| BDBM32017 | |||
| n/a | |||
| Name | BDBM32017 | ||
| Synonyms: | (7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-9-ethanoyl-4-methoxy-6,9,11-tris(oxidanyl)-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-quinone;hydrochloride | (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | (7S,9S)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | DAUNORUBICIN HYDROCHLORIDE | Daunorubicin | MLS000069508 | SMR000058559 | cid_62770 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H29NO10 | ||
| Mol. Mass. | 527.5199 | ||
| SMILES | COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O | ||
| Structure | 
| ||