| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-2 |
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| Ligand | BDBM291232 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | <100±n/a nM |
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| Comments | extracted |
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| Citation |  Sun, Y; Feng, H; Li, Y; Mei, S; Pan, J; Wang, A; Ye, H; Zhang, K Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors US Patent US9580418 Publication Date 2/28/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-2 |
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| Name: | Serine/threonine-protein kinase pim-2 |
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| Synonyms: | PIM2 | PIM2_HUMAN | Pim-2h | Serine/threonine-protein kinase (PIM2) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase pim-2 (PIM2) |
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| Type: | Serine/threonine-protein kinase |
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| Mol. Mass.: | 34185.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9P1W9 |
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| Residue: | 311 |
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| Sequence: | MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAI
KVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPL
PAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKL
IDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFER
DQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKG
GPAPLAWSLLP
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| BDBM291232 |
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| n/a |
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| Name | BDBM291232 |
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| Synonyms: | US9580418, Example 52 | US9890162, Example 52 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H34N6O4 |
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| Mol. Mass. | 554.6395 |
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| SMILES | C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)-c1ccc(OC2CCOCC2)nc1 |r| |
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| Structure | 
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