| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase ABL1 [131-238] |
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| Ligand | BDBM231647 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Assay |
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| pH | 7.25±n/a |
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| Kd | 3.33e+3± 5.3e+2 nM |
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| Comments | extracted |
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| Citation |  Gifford, SM; Liu, W; Mader, CC; Halo, TL; Machida, K; Boggon, TJ; Koleske, AJ Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin. J Biol Chem289:19704-13 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase ABL1 [131-238] |
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| Name: | Tyrosine-protein kinase ABL1 [131-238] |
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| Synonyms: | ABL | ABL1 | ABL1_HUMAN | Abelson tyrosine-kinase 1 SH2 domain (ABL SH2) | JTK7 |
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| Type: | Protein |
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| Mol. Mass.: | 12162.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Truncated human ABL (131-238 aa) |
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| Residue: | 108 |
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| Sequence: | PVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES
RFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEME
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| BDBM231647 |
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| n/a |
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| Name | BDBM231647 |
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| Synonyms: | SSPIpYEDAA | pY421 |
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| Type | Small organic molecule |
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| Emp. Form. | C41H62N9O20P |
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| Mol. Mass. | 1031.953 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(O)=O |r| |
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| Structure | 
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