| Reaction Details |
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 | Report a problem with these data |
| Target | N-acylethanolamine-hydrolyzing acid amidase |
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| Ligand | BDBM50439665 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| pH | 7.4±n/a |
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| IC50 | 18±n/a nM |
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| Comments | extracted |
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| Citation |  Piomelli, D; Bandiera, T; Mor, M; Tarzia, G; Bertozzi, F; Ponzano, S Disubstituted beta-lactones as inhibitors of N-acylethanolamine acid amidase (NAAA) US Patent US9353075 Publication Date 5/31/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| N-acylethanolamine-hydrolyzing acid amidase |
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| Name: | N-acylethanolamine-hydrolyzing acid amidase |
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| Synonyms: | ASAH-like protein | Asahl | N-acylethanolamine acid amidase (NAAA) | N-acylethanolamine-hydrolyzing acid amidase | N-acylethanolamine-hydrolyzing acid amidase (NAAA) | N-acylethanolamine-hydrolyzing acid amidase subunit alpha | N-acylethanolamine-hydrolyzing acid amidase subunit beta | N-acylsphingosine amidohydrolase-like | NAAA_RAT | Naaa |
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| Type: | Enzyme |
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| Mol. Mass.: | 40306.53 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q5KTC7 |
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| Residue: | 362 |
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| Sequence: | MGTPAIRAACHGAHLALALLLLLSLSDPWLWATAPGTPPLFNVSLDAAPELRWLPMLQHY
DPDFVRAAVAQVIGDRVPQWILEMIGEIVQKVESFLPQPFTSEIRGICDYLNLSLAEGVL
VNLAYEASAFCTSIVAQDSQGRIYHGRNLDYPFGNALRKLTADVQFVKNGQIVFTATTFV
GYVGLWTGQSPHKFTISGDERDKGWWWENMIAALSLGHSPISWLIRKTLTESEDFEAAVY
TLAKTPLIADVYYIVGGTSPQEGVVITRDRGGPADIWPLDPLNGAWFRVETNYDHWEPVP
KRDDRRTPAIKALNATGQAHLSLETLFQVLSVFPVYNNYTIYTTVMSAAEPDKYMTMIRN
PS
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| BDBM50439665 |
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| n/a |
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| Name | BDBM50439665 |
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| Synonyms: | CHEMBL2419819 | US9353075, 38 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H21NO4 |
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| Mol. Mass. | 291.3422 |
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| SMILES | C[C@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1 |r| |
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| Structure | 
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