| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-glucuronosyltransferase 2B10 |
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| Ligand | BDBM50090677 |
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| Substrate/Competitor | Diclofenac |
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| Meas. Tech. | UDP-glucuronosyltransferase Activity Assay |
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| IC50 | >3.00e+5±n/a nM |
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| Citation |  Liu, Y; She, M; Wu, Z; Dai, R The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors. J Enzyme Inhib Med Chem26:386-93 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-glucuronosyltransferase 2B10 |
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| Name: | UDP-glucuronosyltransferase 2B10 |
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| Synonyms: | UDB10_HUMAN | UGT2B10 | Uridine-5'-diphosphoglucuronosyltransferase 2B10 |
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| Type: | Enzyme |
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| Mol. Mass.: | 60792.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P36537 |
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| Residue: | 528 |
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| Sequence: | MALKWTTVLLIQLSFYFSSGSCGKVLVWAAEYSLWMNMKTILKELVQRGHEVTVLASSAS
ILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLSEIQKDTFWLPFSQEQEILWAIND
IIRNFCKDVVSNKKLMKKLQESRFDIVFADAYLPCGELLAELFNIPFVYSHSFSPGYSFE
RHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLYFDFWFQIFNMKKWDQFYSEVLG
RPTTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGE
NGVVVFSLGSMVSNMTEERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQND
LLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRVDFNTMS
STDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAH
NLTWFQYHSLDVIGFLLACVATVLFIITKCCLFCFWKFARKGKKGKRD
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| BDBM50090677 |
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| Diclofenac |
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| Name | BDBM50090677 |
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| Synonyms: | 4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide | 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide | CHEMBL1109 | SULFAPHENAZOLE | Sulfabid | Sulphaphenazole | US9180183, Sulfaphenazole |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N4O2S |
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| Mol. Mass. | 314.362 |
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| SMILES | Nc1ccc(cc1)S(=O)(=O)Nc1ccnn1-c1ccccc1 |
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| Structure | 
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