Reaction Details |
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Target | Gag-Pol polyprotein [489-587,Q496K] |
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Ligand | BDBM293324 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Inhibition of HIV Replication |
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pH | 7.55±n/a |
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EC50 | <100±n/a nM |
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Comments | extracted |
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Citation | Kadow, JF; Naidu, BN; Tu, Y Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication US Patent US10106504 Publication Date 10/23/2018 |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587,Q496K] |
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Name: | Gag-Pol polyprotein [489-587,Q496K] |
Synonyms: | HIV-1 Protease Chain A | HIV-1 Protease NL4-3 | POL_HV1N5 | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10823.26 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P12497[489-587,Q496K] |
Residue: | 99 |
Sequence: | PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM293324 |
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n/a |
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Name | BDBM293324 |
Synonyms: | US10106504, Example 61 |
Type | Small organic molecule |
Emp. Form. | C38H42FN3O4 |
Mol. Mass. | 623.7562 |
SMILES | Cc1nc(N)c(-c2ccc3CN(Cc4cccc(F)c4C)CCc3c2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O |r| |
Structure |
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