| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM50329694 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | CA Activity Assay |
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| pH | 7.4±n/a |
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| Ki | 1437±n/a nM |
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| Comments | extracted |
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| Citation |  Balaydin, HT; Durdagi, S; Ekinci, D; Sentürk, M; Göksu, S; Menzek, A Inhibition of human carbonic anhydrase isozymes I, II and VI with a series of bisphenol, methoxy and bromophenol compounds. J Enzyme Inhib Med Chem27:467-75 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM50329694 |
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| n/a |
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| Name | BDBM50329694 |
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| Synonyms: | Bis(3,4-dihydroxyphenyl)methanone | CHEMBL1269420 | hCA inhibitor, 3 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10O5 |
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| Mol. Mass. | 246.2155 |
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| SMILES | Oc1ccc(cc1O)C(=O)c1ccc(O)c(O)c1 |
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| Structure | 
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