| Reaction Details |
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 | Report a problem with these data |
| Target | ETS domain-containing protein Elk-1 |
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| Ligand | BDBM237223 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cell-Based Enzyme Inhibition Assay (ELISA) |
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| IC50 | 1.95e+3±n/a nM |
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| Citation |  Li, QS; Lv, PC; Li, HQ; Lu, X; Li, ZL; Ruan, BF; Zhu, HL Synthesis and biological evaluation of novel N, N'-disubstituted urea and thiourea derivatives as potential anti-melanoma agents. J Enzyme Inhib Med Chem27:708-14 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| ETS domain-containing protein Elk-1 |
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| Name: | ETS domain-containing protein Elk-1 |
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| Synonyms: | ELK1 | ELK1_HUMAN | ETS domain-containing protein (Elk1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 44888.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P19419; phosphorylated |
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| Residue: | 428 |
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| Sequence: | MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL
SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH
AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV
LPSAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGL
GRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEVPPQEGVPARLPAVVMDTAGQAGGH
AASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPGPALTPSLLPTH
TLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVV
LSPGPQKP
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| BDBM237223 |
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| n/a |
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| Name | BDBM237223 |
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| Synonyms: | 1-(4-Fluorophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-phenylthiourea (4b) |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19FN2O2S |
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| Mol. Mass. | 382.451 |
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| SMILES | COc1cc(CN(C(=S)Nc2ccccc2)c2ccc(F)cc2)ccc1O |
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| Structure | 
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