| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 6 |
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| Ligand | BDBM50428400 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Esterase Activity Assay |
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| IC50 | 13440±n/a nM |
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| Citation |  Alp, C; Özsoy, Å¿; Alp, NA; Erdem, D; Gültekin, MS; Küfrevioglu, ÿİ; Sentürk, M; Supuran, CT Sulfapyridine-like benzenesulfonamide derivatives as inhibitors of carbonic anhydrase isoenzymes I, II and VI. J Enzyme Inhib Med Chem27:818-24 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 6 |
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| Name: | Carbonic anhydrase 6 |
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| Synonyms: | CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase |
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| Type: | Enzyme |
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| Mol. Mass.: | 35371.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P23280 |
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| Residue: | 308 |
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| Sequence: | MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN
PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE
ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF
ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS
RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL
DYLRRALN
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| BDBM50428400 |
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| n/a |
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| Name | BDBM50428400 |
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| Synonyms: | CA inhibitor, 2 | CHEMBL182659 | [(4-Methylphenyl)Sulfonyl]Phenylamine |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13NO2S |
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| Mol. Mass. | 247.313 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1 |
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| Structure | 
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