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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Macrophage colony-stimulating factor 1 receptor | ||
| Ligand | BDBM238225 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Fluorescence Polarization Competition Immunoassay | ||
| pH | 7.5±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 0.65±n/a nM | ||
| Comments | extracted | ||
| Citation |  Illig, CR; Ballentine, SK; Chen, J; Desjarlais, RL; Meegalla, SK; Wall, M; Wilson, K Inhibitors of c-fms kinase US Patent US9403804 Publication Date 8/2/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Macrophage colony-stimulating factor 1 receptor | |||
| Name: | Macrophage colony-stimulating factor 1 receptor | ||
| Synonyms: | CSF1R_MOUSE | Csf1r | Csfmr | Fms | Macrophage colony-stimulating factor 1 receptor | Macrophage colony-stimulating factor 1 receptor (c-Fms) | Proto-oncogene c-Fms | ||
| Type: | Protein | ||
| Mol. Mass.: | 109173.45 | ||
| Organism: | Mus musculus (Mouse) | ||
| Description: | P09581 | ||
| Residue: | 977 | ||
| Sequence: |
| ||
| BDBM238225 | |||
| n/a | |||
| Name | BDBM238225 | ||
| Synonyms: | US9403804, 2 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H30N4O4 | ||
| Mol. Mass. | 462.5408 | ||
| SMILES | CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)[C@@]1(O)CC[C@@H](CC1)C(O)=O |r,wU:24.27,28.34,c:5,(-1.59,6.83,;-1.59,5.29,;-.82,6.62,;-.26,4.52,;-.26,2.98,;-1.59,2.21,;-2.93,2.98,;-2.93,4.52,;-1.59,.67,;-2.93,-.1,;-2.93,-1.64,;-1.59,-2.41,;-.26,-1.64,;-.26,-.1,;1.08,.67,;2.41,-.1,;2.41,-1.64,;3.74,.67,;5.21,.19,;6.11,1.44,;5.27,2.75,;3.74,2.21,;5.77,4.21,;6.27,5.67,;-4.26,-2.41,;-5.03,-1.08,;-5.59,-3.18,;-5.59,-4.72,;-4.26,-5.55,;-2.93,-4.72,;-2.93,-3.18,;-4.26,-7.09,;-5.59,-7.86,;-2.93,-7.86,)| | ||
| Structure | 
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