Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Macrophage colony-stimulating factor 1 receptor | ||
Ligand | BDBM238230 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Fluorescence Polarization Competition Immunoassay | ||
pH | 7.5±n/a | ||
Temperature | 298.15±n/a K | ||
IC50 | 0.99±n/a nM | ||
Comments | extracted | ||
Citation | Illig, CR; Ballentine, SK; Chen, J; Desjarlais, RL; Meegalla, SK; Wall, M; Wilson, K Inhibitors of c-fms kinase US Patent US9403804 Publication Date 8/2/2016 | ||
More Info.: | Get all data from this article, Assay Method | ||
Macrophage colony-stimulating factor 1 receptor | |||
Name: | Macrophage colony-stimulating factor 1 receptor | ||
Synonyms: | CSF1R_MOUSE | Csf1r | Csfmr | Fms | Macrophage colony-stimulating factor 1 receptor | Macrophage colony-stimulating factor 1 receptor (c-Fms) | Proto-oncogene c-Fms | ||
Type: | Protein | ||
Mol. Mass.: | 109173.45 | ||
Organism: | Mus musculus (Mouse) | ||
Description: | P09581 | ||
Residue: | 977 | ||
Sequence: |
| ||
BDBM238230 | |||
n/a | |||
Name | BDBM238230 | ||
Synonyms: | US9403804, 28 | ||
Type | Small organic molecule | ||
Emp. Form. | C30H40N6O | ||
Mol. Mass. | 500.6782 | ||
SMILES | CN1CCN(CC1)C1CCC(CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:33,(-.58,-8.85,;-.58,-7.31,;-1.91,-6.54,;-1.91,-5,;-.58,-4.23,;.76,-5,;.76,-6.54,;-.58,-2.69,;-1.91,-1.93,;-1.91,-.38,;-.58,.38,;.76,-.38,;.76,-1.93,;-.58,1.93,;-1.91,2.69,;-1.91,4.23,;-.58,5,;-.58,6.54,;-1.91,7.31,;-1.91,8.85,;-3.24,6.54,;-3.24,5,;-4.72,4.49,;-5.61,5.78,;-4.71,7.02,;-5.2,3.03,;-5.67,1.56,;.76,4.23,;.76,2.69,;2.09,5,;2.09,6.54,;3.43,7.31,;4.76,6.54,;5.16,8.03,;6.25,6.15,;4.76,5,;3.43,4.23,)| | ||
Structure |