| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
|---|
| Ligand | BDBM239157 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Esterase Activity Assay |
|---|
| pH | 7.4±n/a |
|---|
| Ki | 3.76e+3±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Koz, ÿ; Ekinci, D; Perrone, A; Piacente, S; Alankus-Çaliskan, ÿ; Bedir, E; Supuran, CT Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes. J Enzyme Inhib Med Chem28:412-7 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 4 |
|---|
| Name: | Carbonic anhydrase 4 |
|---|
| Synonyms: | CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 35037.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P22748 |
|---|
| Residue: | 312 |
|---|
| Sequence: | MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
PMLACLLAGFLR
|
|
|
|---|
| BDBM239157 |
|---|
| n/a |
|---|
| Name | BDBM239157 |
|---|
| Synonyms: | α-CA inhibitor, 2 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H30O16 |
|---|
| Mol. Mass. | 610.5175 |
|---|
| SMILES | OC1C[C@@H](OCC2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)-c3ccc(O)c(O)c3)[C@@H](O)C(O)[C@@H]2O)C(O)[C@@H](O)C1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
