| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin S |
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| Ligand | BDBM240599 |
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| Substrate/Competitor | US9409882, Z-Val-Val-Arg-AMC |
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| Meas. Tech. | Enzyme Inhibition Assay |
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| pH | 6.5±n/a |
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| IC50 | 0.393±n/a nM |
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| Citation |  Anselm, L; Banner, D; Haap, W; Kuhn, B; Luebbers, T; Peters, J; Spinnler, B Pyridine derivatives US Patent US9409882 Publication Date 8/9/2016 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cathepsin S |
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| Name: | Cathepsin S |
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| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
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| Type: | Protein |
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| Mol. Mass.: | 37507.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25774 |
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| Residue: | 331 |
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| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
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| BDBM240599 |
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| US9409882, Z-Val-Val-Arg-AMC |
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| Name | BDBM240599 |
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| Synonyms: | US9409882, 4 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H23Cl2FN4O5S |
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| Mol. Mass. | 581.443 |
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| SMILES | COc1ccc(c(Cl)c1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)c1ncc(Cl)cc1F)C(=O)NC1(CC1)C#N |r| |
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| Structure | 
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