| Reaction Details |
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 | Report a problem with these data |
| Target | Prothrombin |
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| Ligand | BDBM240793 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Thrombin Amidolytic Assay |
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| pH | 8.4±n/a |
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| Ki | 5020±400 nM |
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| Comments | extracted |
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| Citation |  Markowska, A; Bruzgo, M; Surazynski, A; Midura-Nowaczek, K Tripeptides with non-code amino acids as potential serine proteases inhibitors. J Enzyme Inhib Med Chem28:639-43 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prothrombin |
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| Name: | Prothrombin |
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| Synonyms: | Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin precursor | THRB_HUMAN | Thrombin heavy chain | Thrombin light chain |
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| Type: | Protein |
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| Mol. Mass.: | 70029.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00734 |
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| Residue: | 622 |
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| Sequence: | MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLEREC
VEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHV
NITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQE
CSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASA
QAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETG
DGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI
DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN
DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP
VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST
RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY
GFYTHVFRLKKWIQKVIDQFGE
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| BDBM240793 |
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| n/a |
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| Name | BDBM240793 |
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| Synonyms: | H-D-Ser-Chg-Arg-OH (4) |
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| Type | Small organic molecule |
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| Emp. Form. | C18H34N6O5 |
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| Mol. Mass. | 414.4998 |
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| SMILES | N[C@H](CO)C(=O)N[C@@H](CC(=O)N[C@H](CCCNC(N)=N)C(O)=O)C1CCCCC1 |r| |
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| Structure | 
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