| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione reductase, mitochondrial |
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| Ligand | BDBM50390999 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Glutathione Reductase Activity Assay |
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| pH | 8±n/a |
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| Ki | 28720±n/a nM |
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| IC50 | 48400±n/a nM |
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| Comments | extracted |
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| Citation |  Ekinci, D; Cankaya, M; Gül, Ä°; Coban, TA Susceptibility of cord blood antioxidant enzymes glutathione reductase, glutathione peroxidase and glutathione S-transferase to different antibiotics: in vitro approach. J Enzyme Inhib Med Chem28:824-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione reductase, mitochondrial |
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| Name: | Glutathione reductase, mitochondrial |
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| Synonyms: | GLUR | GRD1 | GSHR_HUMAN | GSR | Glutathione reductase | Glutathione reductase (GR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 56271.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00390 |
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| Residue: | 522 |
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| Sequence: | MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG
AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS
EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP
KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKK
TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD
EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ
GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
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| BDBM50390999 |
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| n/a |
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| Name | BDBM50390999 |
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| Synonyms: | CEFOPERAZONE |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27N9O8S2 |
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| Mol. Mass. | 645.667 |
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| SMILES | CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O |c:26| |
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| Structure | 
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