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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Androgen receptor | ||
| Ligand | BDBM245161 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Transactivation Assay | ||
| Temperature | 310.15±n/a K | ||
| IC50 | 477±n/a nM | ||
| Comments | extracted | ||
| Citation |  Nguyen, D; Künzer, H; Faus Gimenez, H; Bader, B; Köhr, S; Fritsch, M N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal products US Patent US9428460 Publication Date 8/30/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Androgen receptor | |||
| Name: | Androgen receptor | ||
| Synonyms: | ANDR_HUMAN | AR | Androgen Receptor | Androgen receptor (AR) | Androgen receptor/Baculoviral IAP repeat-containing protein 2 | DHTR | Dihydrotestosterone receptor | NR3C4 | Nuclear receptor subfamily 3 group C member 4 | ||
| Type: | Receptor | ||
| Mol. Mass.: | 99185.27 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | CHO cells were stably transfected with human AR gene. | ||
| Residue: | 920 | ||
| Sequence: |
| ||
| BDBM245161 | |||
| n/a | |||
| Name | BDBM245161 | ||
| Synonyms: | US9428460, 17 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H20BrFN2O2 | ||
| Mol. Mass. | 443.309 | ||
| SMILES | Fc1ccc(cc1)C(=O)N[C@H]1CC[C@@H](CC1)Oc1ccnc2c(Br)cccc12 |r,wU:13.17,wD:10.10,(7.34,6.93,;6,6.16,;6,4.62,;4.67,3.85,;3.33,4.62,;3.33,6.16,;4.67,6.93,;2,3.85,;.67,4.62,;2,2.31,;.67,1.54,;-.67,2.31,;-2,1.54,;-2,,;-.67,-.77,;.67,,;-3.33,-.77,;-3.33,-2.31,;-2,-3.08,;-2,-4.62,;-3.33,-5.39,;-4.67,-4.62,;-6,-5.39,;-6,-6.93,;-7.34,-4.62,;-7.34,-3.08,;-6,-2.31,;-4.67,-3.08,)| | ||
| Structure | 
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