| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 13 |
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| Ligand | BDBM50329826 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Thermal Shift Assay (TSA) |
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| pH | 7±n/a |
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| Kd | 370±n/a nM |
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| Comments | extracted |
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| Citation |  Zubriene, A; Capkauskaite, E; Gylyte, J; Ki?onaite, M; Tumkevicius, S; Matulis, D Benzenesulfonamides with benzimidazole moieties as inhibitors of carbonic anhydrases I, II, VII, XII and XIII. J Enzyme Inhib Med Chem29:124-31 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 13 |
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| Name: | Carbonic anhydrase 13 |
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| Synonyms: | CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29445.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8N1Q1 |
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| Residue: | 262 |
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| Sequence: | MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKII
SNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELH
VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNF
DLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAA
FLVSNHRPPQPLKGRKVRASFH
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| BDBM50329826 |
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| n/a |
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| Name | BDBM50329826 |
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| Synonyms: | 2-Chloro-5-[(2-isopropyl-1H-benzimidazol-1-yl)acetyl]benzenesulfonamide | CHEMBL1271477 | N-alkylated benzimidazole derivative, 4h |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18ClN3O3S |
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| Mol. Mass. | 391.872 |
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| SMILES | CC(C)c1nc2ccccc2n1CC(=O)c1ccc(Cl)c(c1)S(N)(=O)=O |
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| Structure | 
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