| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-1 |
|---|
| Ligand | BDBM249064 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro Cell Proliferation Potency Assay |
|---|
| IC50 | 425±n/a nM |
|---|
| Citation |  Do, S; Hu, H; Kolesnikov, A; Tsui, VH; Wang, X 5-azaindazole compounds and methods of use US Patent US9434725 Publication Date 9/6/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase pim-1 |
|---|
| Name: | Serine/threonine-protein kinase pim-1 |
|---|
| Synonyms: | PIM1_MOUSE | Pim-1 | Pim1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 44550.25 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | P06803 |
|---|
| Residue: | 313 |
|---|
| Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVAD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSDFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRG
EIKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIKGQVFFRQTVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWMQGDLLPQAAS
EIHLHSLSPGSSK
|
|
|
|---|
| BDBM249064 |
|---|
| n/a |
|---|
| Name | BDBM249064 |
|---|
| Synonyms: | US9434725, 295 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H23N7O |
|---|
| Mol. Mass. | 401.4643 |
|---|
| SMILES | COC1(CCCNC1)c1cccc(n1)-n1ncc2cnc(cc12)-c1cncc(C)n1 |
|---|
| Structure | 
|
|---|
Search and Browse
