| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-1 |
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| Ligand | BDBM249070 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Cell Proliferation Potency Assay |
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| IC50 | 781±n/a nM |
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| Citation |  Do, S; Hu, H; Kolesnikov, A; Tsui, VH; Wang, X 5-azaindazole compounds and methods of use US Patent US9434725 Publication Date 9/6/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Serine/threonine-protein kinase pim-1 |
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| Name: | Serine/threonine-protein kinase pim-1 |
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| Synonyms: | PIM1_MOUSE | Pim-1 | Pim1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 44550.25 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P06803 |
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| Residue: | 313 |
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| Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVAD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSDFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRG
EIKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIKGQVFFRQTVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWMQGDLLPQAAS
EIHLHSLSPGSSK
|
|
|
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| BDBM249070 |
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| n/a |
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| Name | BDBM249070 |
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| Synonyms: | US9434725, 301 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N8O |
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| Mol. Mass. | 416.479 |
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| SMILES | OCCCc1cncc(n1)-c1cc2n(ncc2cn1)-c1cccc(n1)N1CCNCC1 |
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| Structure | 
|
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