| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
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| Ligand | BDBM251678 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Receptor Assay |
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| Temperature | 310.15±n/a K |
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| IC50 | 2±n/a nM |
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| Comments | extracted |
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| Citation |  Buffham, W; Canning, H; Davenport, R; Farnaby, W; Mack, S; Parmar, A; Wright, S Compounds US Patent US9464060 Publication Date 10/11/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 1 |
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| Name: | Lysophosphatidic acid receptor 1 |
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| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41120.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92633 |
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| Residue: | 364 |
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| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
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| BDBM251678 |
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| n/a |
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| Name | BDBM251678 |
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| Synonyms: | US10100018, Example 14 | US9464060, 14 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H24FNO5 |
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| Mol. Mass. | 485.503 |
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| SMILES | COc1ccc(CN(Cc2ccc(cc2)C(O)=O)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 |
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| Structure | 
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