Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Amine oxidase [flavin-containing] A | ||
| Ligand | BDBM254581 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Fluorescence-Based (Inhibitor)-Screening Assay | ||
| pH | 7.5±n/a | ||
| Temperature | 310.15±n/a K | ||
| IC50 | >100000±n/a nM | ||
| Comments | extracted | ||
| Citation |  Ortega Muñoz, A; Fyfe, MC; Martinell Pedemonte, M; Estiarte Martínez, M; Valls Vidal, N; Kurz, G; Castro Palomino Laria, JC (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors US Patent US9469597 Publication Date 10/18/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Amine oxidase [flavin-containing] A | |||
| Name: | Amine oxidase [flavin-containing] A | ||
| Synonyms: | AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) | ||
| Type: | Protein | ||
| Mol. Mass.: | 59689.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21397 | ||
| Residue: | 527 | ||
| Sequence: |
| ||
| BDBM254581 | |||
| n/a | |||
| Name | BDBM254581 | ||
| Synonyms: | US10214477, Example 40 | US9469597, 40 | US9670136, 40 N1-((trans)-2-(4-cyclopropylphenyl)cyclopropyl)cyclohexane-1,4-diamine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H26N2 | ||
| Mol. Mass. | 270.4124 | ||
| SMILES | NC1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(cc1)C1CC1 |r,wU:10.12,wD:8.8,(7.54,3.36,;6.21,2.59,;6.21,1.05,;4.87,.28,;3.54,1.05,;3.54,2.59,;4.87,3.36,;2.21,.28,;.87,1.05,;.1,2.39,;-.67,1.05,;-2,.28,;-3.33,1.05,;-4.67,.28,;-4.67,-1.26,;-3.33,-2.03,;-2,-1.26,;-6,-2.03,;-7.54,-2.03,;-6.77,-3.36,)| | ||
| Structure | 
| ||