Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Amine oxidase [flavin-containing] B | ||
Ligand | BDBM256666 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibitory Activity Assay | ||
pH | 7.5±n/a | ||
Temperature | 298.15±n/a K | ||
IC50 | >100000±n/a nM | ||
Comments | extracted | ||
Citation | Matsumoto, S; Hattori, Y; Toyofuku, M; Morimoto, S; Daini, M; Kojima, T; Kaku, T; Ito, M Cyclopropanamine compound and use thereof US Patent US9487511 Publication Date 11/8/2016 | ||
More Info.: | Get all data from this article, Assay Method | ||
Amine oxidase [flavin-containing] B | |||
Name: | Amine oxidase [flavin-containing] B | ||
Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) | ||
Type: | Protein | ||
Mol. Mass.: | 58768.76 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P27338 | ||
Residue: | 520 | ||
Sequence: |
| ||
BDBM256666 | |||
n/a | |||
Name | BDBM256666 | ||
Synonyms: | BDBM256667 | US9487511, 45 | ||
Type | Small organic molecule | ||
Emp. Form. | C20H29F2N3OS | ||
Mol. Mass. | 397.526 | ||
SMILES | NC1CCC(CC1)N[C@@H]1C[C@@H]1c1cc(cs1)C(=O)NC1CCC(F)(F)CC1 |r,wD:8.8,10.12,(10.15,-.4,;8.66,-.8,;8.26,-2.29,;6.78,-2.69,;5.69,-1.6,;6.08,-.11,;7.57,.29,;4.2,-1.99,;3.11,-.91,;2.02,-1.99,;1.62,-.51,;.53,.58,;-.93,.11,;-1.84,1.35,;-.93,2.6,;.53,2.12,;-3.38,1.35,;-4.15,2.69,;-4.15,.02,;-5.69,.02,;-6.78,1.11,;-8.26,.71,;-8.66,-.78,;-10.15,-1.18,;-9.75,.31,;-7.57,-1.87,;-6.08,-1.47,)| | ||
Structure |