| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 4 [75-147] |
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| Ligand | BDBM259897 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 27.1±n/a nM |
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| Citation |  Durden, DL; Morales, GA; Garlich, JR Thienopyranones as kinase and epigenetic inhibitors US Patent US9505780 Publication Date 11/29/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 4 [75-147] |
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| Name: | Bromodomain-containing protein 4 [75-147] |
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| Synonyms: | BRD4 | BRD4_HUMAN | Bromo domain 1 | Bromodomain-containing protein 4 (BD1) | Bromodomain-containing protein 4 (BRD4) Bromo 1 | Bromodomain-containing protein 4 (BRD4)(BD1) | Bromodomain-containing protein 4 (BRD4)(Bromo 1) | Bromodomain-containing protein 4 Bromo 1 domain(BRD4 BD1) | Bromodomain-containing protein 4 Bromodomain 1 (BRD4-1) | Bromodomain-containing protein 4 Domain 1 | HUNK1 |
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| Type: | n/a |
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| Mol. Mass.: | 8856.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | BD1 (75-147 aa) of O60885 |
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| Residue: | 73 |
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| Sequence: | WKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFT
NCYIYNKPGDDIV
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| BDBM259897 |
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| n/a |
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| Name | BDBM259897 |
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| Synonyms: | US9505780, JQ-1 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23ClN4O2S |
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| Mol. Mass. | 442.962 |
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| SMILES | Cc1nnc2[C@@H](N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1)C(=O)OC(C)(C)C |c:6| |
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| Structure | 
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