| Reaction Details |
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 | Report a problem with these data |
| Target | Low molecular weight phosphotyrosine protein phosphatase |
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| Ligand | BDBM50054344 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 2340±20 nM |
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| Citation |  Zhang, Z; Zeng, L Hydroxyindole carboxylic acid based inhibitors for oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) US Patent US9522881 Publication Date 12/20/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Low molecular weight phosphotyrosine protein phosphatase |
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| Name: | Low molecular weight phosphotyrosine protein phosphatase |
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| Synonyms: | 3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c |
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| Type: | n/a |
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| Mol. Mass.: | 18042.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24666 |
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| Residue: | 158 |
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| Sequence: | MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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| BDBM50054344 |
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| n/a |
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| Name | BDBM50054344 |
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| Synonyms: | CHEMBL3319356 | US9522881, 11a-1 L97M74 | US9844535, ID 11a-1 L97M74 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H20IN3O5S |
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| Mol. Mass. | 637.445 |
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| SMILES | Cn1c(c(I)c2cc(C(O)=O)c(O)cc12)-c1cccc(NC(=O)C(=O)Nc2ccc(cc2)-c2ccsc2)c1 |
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| Structure | 
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